Not just a stem cell marker
Jan 21, 2018
The protein CD34 is predominantly regarded as a marker of blood-forming stem cells but it helps with migration to the bone marrow too.
Results for human health
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Computer models combat malaria
Apr 15, 2018
A new malaria metabolic model may uncover better ways to treat a highly deadly disease.
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The dynamic molecular changes of homing
Aug 5, 2018
Molecules reorganize to slow stem cells down, giving them a chance to adhere to and eventually cross the inner lining of blood vessels into the bone marrow.
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Turning up the heat on pathogenic bacteria
Jun 16, 2019
Protein found in gut-dwelling pathogens changes shape under human body temperatures, leading to toxins responsible for diarrheal disease.
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Database to support infectious disease research
Sep 11, 2019
Linking disease pathogens to clinical signs and symptoms through a database could support research into the molecular mechanisms of infectious diseases.
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Plastic biosensor finds sweet success
Dec 16, 2019
Medical diagnostic device extracts energy from sugars naturally present in the body to drive its glucose-sensing circuitry.
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LD Motif Finder locates ancient hidden protein patterns
Jan 6, 2020
A machine learning method has identified highly elusive amino acid sequences involved in cell morphogenesis and adhesion and in diseases like cancer.
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Algorithm turns cancer gene discovery on its head
Jan 20, 2020
Prediction method could help personalize cancer treatments and reveal new drug targets.
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Spotting cancer's greasy fingerprints
Jan 26, 2020
Laser-based microscopes can tune into multiple biomolecular signatures found in cancer cells.
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Iron nanorobots show their true mettle
Jan 28, 2020
Multifunctional iron nanowires selectively obliterate cancer cells with a triple-punch combination attack.
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Powering devices goes skin deep
Mar 8, 2020
A way to remotely charge batteries through flesh could help develop components for permanent implantable medical devices.
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Silkworms provide new spin on sticky molecules
Mar 16, 2020
E-selectin is grown in silkworms for the first time, revealing new aspects of its binding dynamics.
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Jumping genes help make neurons in a dish
Mar 26, 2020
The conversion of skin cells into brain cells relies on proper insertion of L1 elements.
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Untangling untidy folds to understand diseases
Apr 12, 2020
Copper ions could play a key role when peptide folding goes wrong and leads to harmful aggregates.
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Sensing a heart attack before it strikes
Apr 13, 2020
Nanomaterial-based electronic device monitors a key heart health biomarker.
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Clocking in with malaria parasites
Jun 9, 2020
Discovery of a malaria parasite’s internal clock could lead to new treatment strategies
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A salt solution toward better bioelectronics
Jun 14, 2020
A water-stable dopant enhances and stabilizes the performance of electron-transporting organic electrochemical transistors.
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Studying COVID-19’s envelope protein
Jul 27, 2020
A likeness between genes of the SARS and COVID-19 viruses could inform research into potential treatments.
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Enzyme biofactories to enhance cord blood transplants
Oct 21, 2020
Stem cell trafficking to the bone marrow is improved by an enzyme manufactured in silkworms and yeast.
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For quick COVID-19 testing, iSCAN can
Nov 3, 2020
A new test kit could enable quick and effective COVID-19 tests for people arriving at airports.
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Deep learning in the emergency department
Nov 22, 2020
Harnessing the power of deep learning leads to better predictions of patient admissions and flow in emergency departments.
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Biobank of stem cells helps understand genetic abnormalities
Jan 26, 2021
A database of newly generated stem cell lines could provide the key to understanding the genetic factors that drive Klinefelter syndrome and related diseases.
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Get a load of ZIF! Better delivery of cancer immunotherapy
Feb 11, 2021
An antibody loaded onto a porous metal organic framework is released by the acidic environment that surrounds tumors, avoiding the adverse effects of administering the antibody alone.
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CovMT: Tracking virus mutations across the world
Feb 21, 2021
An interactive platform helps users visualize where SARS-CoV-2 mutations start, how wide they spread and how infectious they are.
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Virus detection method is versatile and accessible
Feb 25, 2021
A low-cost diagnostic tool can detect a range of viruses without the need for expensive materials or facilities.
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Enzymatic danse macabre of lung cancer
Mar 15, 2021
A mutational change of an enzyme’s dynamics increases its activity on a chromatin histone, ultimately causing a common lung cancer.
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Ultrashort peptides go a long way for tissue engineering
Apr 4, 2021
A printable hydrogel made of ultrashort peptides could help shape cells into viable tissues.
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All-in-one test for COVID-19 surveillance
Apr 20, 2021
New method can simultaneously diagnose cases, track variants and detect co-infections.
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Elegant constrictions in a cellular kill switch
May 4, 2021
Combining expertise has shed new light on how cells self-destruct during microbial infection.
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Coronavirus testing made quick and easy
May 26, 2021
New diagnostic technique could help contain the spread of COVID-19 and other viral outbreaks.
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Genetic treasure trove for malaria researchers
May 30, 2021
Detailed and extensive genome sequencing of a subspecies of rat-infecting malaria parasites should instruct human malaria research.
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Feeling hot and bothered? It's complicated
Jun 8, 2021
Trends in heat discomfort are more subtle than expected across Saudi Arabia and beyond.
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Predicting the evolution of a pandemic
Jun 15, 2021
An extended epidemic model that accounts for uncertainty and the latest data can better predict the evolution of pandemics.
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Skeletal scaffold supports bone cells and blood vessels
Jun 17, 2021
3D models of bone formation provide a tool for tissue engineering, biomedical research and drug testing.
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Keeping a vigilant watch on SARS-CoV-2
Jun 20, 2021
New lateral flow test Vigilant is cheaper, easier to use and as reliable as the current gold standard PCR test for diagnosing SARS-CoV-2 infection.
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Viruses as communication molecules
Jun 23, 2021
Electrical and computer engineers take on complex modeling questions that can further our understanding of virus spread in small spaces.
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Gel drops for regenerative medicine
Aug 8, 2021
Tiny drops that resemble an extracellular matrix can be used to culture cells for delivery into the human body.
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Stem cell model for early human embryo development
Sep 8, 2021
An in vitro cellular model that mimics the initial phase of human embryo creation could improve understanding of infertility.
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Airborne antennas to address EMF concerns
Oct 3, 2021
Movable airborne antennas receiving cellphone signals could reduce EMF exposure while offering higher data transmission speed and using less power.
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The complex dynamics of stem cell tethers and slings
Oct 6, 2021
Molecules move within elongated protrusions to help stabilize migrating cells inside the bloodstream.
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DNA replication under the microscope
Nov 21, 2021
The three-dimensional structure of a protein complex that is key for replicating damaged DNA offers insights into its regulation.
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Compact CRISPR system enables portable COVID-19 testing
Nov 28, 2021
Miniature RNA-cutting protein harnessed for diagnostics and therapeutics.
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Finding true protein hotspots in cancer research
Dec 8, 2021
Novel statistical methods help tell the difference between "false positives" and true detections of protein domain hotspots that could be linked to cancer.
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Ramping up point-of-care diagnosis for COVID-19 and beyond
Dec 14, 2021
Transistor-based sensors offer hope for rapid diagnosis and treatment for COVID-19 and other infections.
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Picture perfect X-ray capture
Dec 15, 2021
Layered nanomaterials shine for lossless light-energy conversion.
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Getting to the bottom of deadly weather
Jan 5, 2022
Cold still causes far more deaths than heat in India.
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Silencing tool quashes gene activity across generations
Feb 3, 2022
Genomic defense mechanism harnessed to manipulate gene activity in worms.
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Disease severity linked to N protein of SARS-CoV-2
Mar 27, 2022
Insight into the function of the nucleocapsid protein could help develop drugs that reduce coronavirus impact.
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Studying the genes behind surplus X chromosomes
Mar 29, 2022
Stem cell analyses could reveal how extra doses of some genes lead to the characteristics seen in males born with one or more surplus X chromosomes.
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Good gene therapy comes in small packages
Apr 10, 2022
Hybrid material helps ferry genetic cargo to target cells.
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Can machine learning help predict disease spread?
Apr 17, 2022
Machine learning techniques used to analyze case data show promise for predicting the evolution of an epidemic.
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AI helps diagnose post-COVID lung problems
May 24, 2022
Tool reveals hidden features on chest scan images.
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New database to "SpUR" on cancer research
May 26, 2022
An online tool reveals the extent of gene-restructuring events in noncoding sequences.
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Extreme analysis of seizures
Jun 20, 2022
The statistics of extreme events helps to better understand epileptic seizures.
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Bone formation comes down to the nanowire
Jun 28, 2022
Nanotechnology that accelerates the transition of stem cells into bone could advance regenerative medicine.
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Turning up the heat to unlock Cas13's potential
Jun 29, 2022
A newly identified heat-stable Cas13 enzyme could lead to improved diagnostics and new biotechnological applications.
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Stem cells reveal underpinnings of rare immune disease
Jul 3, 2022
Abnormal protein tied to Wiskott-Aldrich syndrome found to control gene splicing.
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Cell mapping close to the bone
Aug 16, 2022
Deep molecular analysis of the bone marrow microenvironment reveals that the cells regulating blood stem cell maintenance are more diverse than expected and have features likely to be conserved between species.
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"Sticky" stem cells make for better transplants
Aug 24, 2022
Enhancement of adhesion molecules improves the ability of blood-forming stem cells to take root in transplant recipients.
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Harnessing the power of saffron color for food and future therapeutics
Aug 31, 2022
A highly efficient enzyme combined with a multigene engineering approach offers potential for sustainable production of water-soluble pigments in plant tissues.
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Anthropogenic air pollution impacts health and climate in the Middle East
Sep 22, 2022
Modeling air quality over the Arabian Peninsula reveals that pollution from anthropogenic sources is contributing to health risks and climate change.
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Finding an RNA target and tool to fight premature aging
Oct 4, 2022
Blocking the overexpression of specific repeat RNA sequences could prove promising for the treatment of premature aging syndromes.
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Complex regulation controls mediator of cancer growth
Oct 9, 2022
Elaborate interaction discovered between epigenetic regulatory protein and its activating lipid partner.
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Zinc enhances albumin’s protective role against Parkinson's disease
Oct 16, 2022
Revealing zinc’s interaction with a critical transport protein underscores the need to study biological pathways under physiologically relevant conditions.
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Bacterial quorum quenched by bacterial enzyme
Oct 18, 2022
An enzyme from a Red Sea bacterium suppresses the formation of a slimy biofilm that helps propagate hospital-acquired infections.
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A skewed model for imbalanced health data
Nov 7, 2022
An asymmetric statistical model provides a better fit for imbalanced data with rare "positives," such as longitudinal health datasets.
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Reflecting on a shift in "rainbow" sensors
Nov 20, 2022
Nanostructured surfaces enable lab-on-a-chip lung cancer diagnosis.
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Cryptic drug-binding sites discovered in the dance
Nov 21, 2022
Studying the molecular motion of proteins reveals previously unseen binding sites that could be targeted by new drug candidate molecules.
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Explaining the DNA repair mechanism
Dec 8, 2022
Better understanding of the mechanisms involved in DNA repair may pave the way for developing inhibitors to improve the effectiveness of radiation therapy.
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Fastening enzyme seals the deal in genome repair
Jan 24, 2023
Structural biology study reveals dynamics of DNA ligation during genome replication.
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Memory formed alongside brain signaling system
Feb 13, 2023
Evolution of lactate-mediated nerve signaling probably enabled memory systems, a comparative gene study shows.
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Double treatment stores salmon and strawberries for later
Feb 21, 2023
Combining UV sterilization with vacuum sealing significantly extends the shelf-life of a variety of foods.
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RNA: Don't kill the messenger
Mar 8, 2023
A newly found protein complex plays a vital role in RNA protection and stability during its journey between DNA and the cell’s protein factory.
