Making the silent genes speak
Dec 13, 2014
Regulating an overlooked set of genes may help biologists manipulate cells to find new therapy options.
Results for genomics
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Parasite scan yields new targets
Dec 20, 2014
Enzymes crucial to parasite growth offer clues in fight against malaria.
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Molecular movie reveals enzyme’s mechanism of action
Dec 24, 2014
An enzyme involved in maintaining genome fidelity goes through seven steps to recognize its DNA substrates.
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Herbicide resistance: shedding light on the shikimate pathway
Dec 26, 2014
Resistance to a popular herbicide provides insight into the control of a key biosynthetic pathway.
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How extremophiles handle the briny deep
Dec 26, 2014
Single-cell analysis of microbes from Red Sea deep brine pools reveals the genetic innovations needed to thrive in extreme conditions.
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Decoding noncoding sequences
Feb 6, 2015
Evolution has left alone the protective functions of noncoding sequences of the human genetic blueprint.
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Growing on salty soils
Feb 6, 2015
KAUST Center for Desert Agriculture leads research to improve crop yields from desert soils.
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Sequencing reveals strains behind cholera outbreak
Mar 28, 2015
Whole-genome sequencing of the bacterium responsible for a cholera outbreak reveals a population structure missed by traditional methods.
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Finding patterns in big data
May 9, 2015
A statistical approach that can find patterns in large data sets, even in the event of missing or incorrect figures, is proving useful from genomic studies through to planning a marine reserve.
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Pathogens hitch a lift on host’s metabolism
May 26, 2015
A new computational framework shows how pathogens interact with host cells at the metabolic level.
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Sensing for sustainable agriculture
Aug 22, 2015
Novel use of sensors and associated high-resolution imaging in agriculture aims to facilitate a more sustainable future.
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Honey bee behavior is in the genes
Aug 22, 2015
An integrated set of genetic mechanisms controls whether bees behave as foragers or nurses.
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A model for coral-algae relationships
Sep 12, 2015
Analysis of sea anemone genome yields unprecedented detail of anemone-algae symbiosis, and may provide a model for coral symbiosis.
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Doubled up protein protects against cancer
Sep 26, 2015
Insight into additional functions of a key cancer protein could pave the way for new anti-cancer drugs.
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Molecular immunity from microbes
Nov 10, 2015
Harnessing a bacterial system of defense can protect plants against viral pathogens.
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Pathogen expertise boosted with latest genomics
Feb 13, 2016
Expert knowledge in the field of DNA and RNA sequencing puts KAUST at the forefront of high-impact pathogen research.
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From head to tail in search of piRNAs
May 14, 2016
Small non-coding RNAs thought to be found in testes are also present in the adult mouse brain.
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Exploring protein form to find function
Jun 25, 2016
Existing systems for predicting protein structure are outperformed by a newly developed method.
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Enhancing understanding of genetic regulation
Aug 13, 2016
Researchers round up clues to track down enhancers.
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The first genome of a coral reef fish
Sep 24, 2016
A genome for the blacktail butterflyfish may illustrate how reef fish adapt to challenging conditions in the Red Sea.
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Exploring how rice could survive salt stress
Nov 16, 2016
Real-time genetic detailing of rice plants highlights the roles of different loci in response to salt stress during growth.
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Clownfish adapt for population survival
Dec 17, 2016
Identification of candidate pathways in clownfish shows they can control responses to population alterations.
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The intersection of folding and function
Jan 14, 2017
The dynamic three-dimensional organization of chromosomal structure can profoundly influence plant gene expression.
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A new path to fixing genes in living organisms
Jan 28, 2017
A gene-editing method shows promise for using targeted gene-replacement therapy in living organisms.
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Quinoa—quest to feed the world
Feb 7, 2017
The high-quality sequencing of a quinoa genome brings new potential for global food security.
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Tracking superbugs for antibiotic resistance
Feb 11, 2017
An antibiotic resistant strain of bacteria found circulating in Jeddah’s municipal wastewater could have severe implications for public health.
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Gene sequences reveal secrets of symbiosis
Feb 18, 2017
Genome sequences of dinoflagellate algae indicate how they maintain their symbiotic relationship with corals.
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First detection of an artemisinin-resistant malaria parasite contracted in Africa
Feb 21, 2017
Africa now joins Southeast Asia in hosting parasites partially resistant to the first-line antimalaria drug, artemisinin.
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The carpenter enzyme gives DNA the snip
Apr 1, 2017
Enzyme follows a two-step verification system before cutting and repairing DNA damage.
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Tweaking the transcriptome to tackle stress
Apr 15, 2017
Stressed dinoflagellates rewrite their genes during transcription.
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Finding Nemo’s genes: reef fish genome mapped and shared
May 20, 2018
Nemo’s genome has been deciphered and made publicly available, helping researchers further investigate fish ecology and evolution.
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Coral tricks for adapting to ocean acidification
Jun 7, 2018
A molecular process that signals distress could also help corals adapt to climate change.
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Mining Red Sea bacteria for industrial potential
Oct 4, 2018
Genome sequencing of two Red Sea bacteria highlights their potential as industrial workhorses.
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Global study links newly named syndrome with other disorders
May 16, 2019
Mutations in a repetitive protein motif are responsible for a rare cognitive disorder.
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Directed evolution comes to plants
Jun 19, 2019
Accelerating plant evolution with CRISPR paves the way for breeders to engineer new crop varieties.
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Quenching scientific curiosity with single-molecule imaging
Jul 24, 2019
New experimental insights allow researchers to probe protein-DNA interactions with greater precision.
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Argonaute proteins help fine-tune gene expression
Oct 27, 2019
A protein, with a name reminiscent of legendary Greek sailors, has an unexpected role inside the human nucleus.
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Better plant edits by enhancing DNA repair
Apr 5, 2020
A protein hijacked from a bacterial pathogen helps to facilitate more precise genome editing in plants.
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Fish flip a unique genetic switch in warming seas
Apr 22, 2020
Reef fish species uniquely respond to climate change, with some more vulnerable than others.
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Clocking in with malaria parasites
Jun 9, 2020
Discovery of a malaria parasite’s internal clock could lead to new treatment strategies
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Studying COVID-19’s envelope protein
Jul 27, 2020
A likeness between genes of the SARS and COVID-19 viruses could inform research into potential treatments.
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Barcoding long DNA quantifies CRISPR effects
Aug 26, 2020
A sequencing approach can home in on a rare mutation within a large number of cells, revealing implications for CRISPR genome editing and early cancer detection.
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Better communication helps translate molecular tools
Sep 15, 2020
Multistakeholder collaboration is key for the adoption of molecular approaches that can facilitate accurate, cheaper and faster monitoring of marine ecosystems.
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Genetic gains for better grains
Sep 29, 2020
A nutritious millet crop grown mainly in West Africa could be genetically improved for large-scale agriculture in Saudi Arabia.
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Cauliflower coral genome sequenced
Oct 27, 2020
A newly sequenced coral genome offers tools to understand environmental adaptation.
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Simulating evolution to understand a hidden switch
Jan 15, 2021
Some organisms evolve an internal switch that can remain hidden for generations until stress flicks it on.
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Biobank of stem cells helps understand genetic abnormalities
Jan 26, 2021
A database of newly generated stem cell lines could provide the key to understanding the genetic factors that drive Klinefelter syndrome and related diseases.
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Rules of resistance against transgene silencing
Jan 28, 2021
A new protocol brings the precise standards of engineering to the realm of synthetic biology.
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Atomic techniques reveal the evolution of a bacterial protein
Mar 21, 2021
Researchers show how bacteria have adapted a sensing mechanism that allows them to live in different environments.
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How reef-building corals got their bones
Apr 29, 2021
Coral ancestors had the genetic toolkit to make skeletal structures and only took simple evolutionary steps to begin building reefs.
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Coral symbionts have a genome like no other
Apr 29, 2021
The weird and wonderful genome of dinoflagellates looks nothing like other eukaryotic genomes.
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Genetic treasure trove for malaria researchers
May 30, 2021
Detailed and extensive genome sequencing of a subspecies of rat-infecting malaria parasites should instruct human malaria research.
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Into the belly of the bee
Jun 13, 2021
Honeybees bring back more than just nectar from their floral feasts and these microbes may help them survive turbulent times.
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Keeping a vigilant watch on SARS-CoV-2
Jun 20, 2021
New lateral flow test Vigilant is cheaper, easier to use and as reliable as the current gold standard PCR test for diagnosing SARS-CoV-2 infection.
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Creating a lab mangrove helps to identify new bacteria
Jul 7, 2021
Honing a growth chamber cultivation technique leads to the identification of novel bacteria from Red Sea mangrove sediments.
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Equalizing the microbial research playing field
Jul 29, 2021
An approach that reduces the computational power required to analyze huge amounts of DNA data for identifying new microbes and their proteins could be used for manufacturing anything from new antibiotics to plastic-degrading enzymes.
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Silencing tool quashes gene activity across generations
Feb 3, 2022
Genomic defense mechanism harnessed to manipulate gene activity in worms.
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Studying the genes behind surplus X chromosomes
Mar 29, 2022
Stem cell analyses could reveal how extra doses of some genes lead to the characteristics seen in males born with one or more surplus X chromosomes.
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Coral genome reveals cysteine surprise
Sep 23, 2022
The generation of a high-quality genome from a coral specimen reveals an alternative pathway for cysteine biosynthesis in animals and cautions against overreliance on model organisms.
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Finding an RNA target and tool to fight premature aging
Oct 4, 2022
Blocking the overexpression of specific repeat RNA sequences could prove promising for the treatment of premature aging syndromes.
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Complex regulation controls mediator of cancer growth
Oct 9, 2022
Elaborate interaction discovered between epigenetic regulatory protein and its activating lipid partner.
